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August 18, 2020

Journal of Investigative Dermatology Highlights Data from LEO Science & Tech Hub Partnership with Epicore Biosystems, Inc.

The Journal of Investigative Dermatology (JID) recently published “Rapid Capture and Extraction of Sweat for Regional Rate and Cytokine Composition Analysis Using a Wearable Soft Microfluidic System”

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Tuesday, August 18, 2020

The Journal of Investigative Dermatology (JID) recently published “Rapid Capture and Extraction of Sweat for Regional Rate and Cytokine Composition Analysis Using a Wearable Soft Microfluidic System”

The Journal of Investigative Dermatology (JID) recently published “Rapid Capture and Extraction of Sweat for Regional Rate and Cytokine Composition Analysis Using a Wearable Soft Microfluidic System” in its Letters to the Editor.

The article highlights a study involving Epicore Biosystems, Inc.’s soft, skin-interfaced microfluidic patch in development to enable rapid capture and extraction of sweat volumes for the analysis of cytokines.

Epicore Biosystems, Inc. is a LEO Science & Tech Hub partner and a wearable solutions spinout from Northwestern University’s Querrey-Simpson Institute for Bioelectronics. The partnership advances the development of Epicore Biosystems’ wearable Discovery patch and electrochemical sensors to measure prognostic skin health and inflammation biomarkers. The goal is to explore if and how these biochemical markers may apply to and inform treatment decisions.

This initial study highlighted in JID was completed in June 2019 in collaboration with Northwestern University dermatologists to establish baseline data using the Discovery platform and to test its clinical utility.

Patches were skin mounted on 10 healthy individuals to collect sweat when individuals were exposed to heat in a controlled environment.

Concentrations of three cytokines – IL-1α, IL-1RA, and IL-8 – were assessed twice a day and on consecutive days. The team demonstrated the ability to quantify the concentrations of target inflammation biomarkers in sweat across different skin locations.

Learn more about the study findings and Epicore Biosystems.

MAT-37562. August 2020.

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